Uptake of Photosensitizer by Human Atheromatous Plaques
نویسندگان
چکیده
منابع مشابه
Ruptured Atheromatous Plaques
Although early occlusion of saphenous vein coronary artery bypass grafts is usually thrombotic, late occlusion is most often a result of progressive intimal fibromuscular proliferation or atheroma formation in the implanted vein. We describe another mechanism of late graft occlusion: atheromatous plaque rupture with superimposed occlusive thrombosis. Four men, ages 48-67 years underwent repeat ...
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Monocytes appear to be central to atherogenesis both as the progenitors of foam cells and as a potential source of growth factors mediating intimal hyperplasia, but the chemical messages which stimulate the influx of monocytes into human atheroma remain unknown. Monocyte chemoattractant protein-1 (MCP-1) is a recently described molecule with powerful monocyte chemotactic activity expressed by m...
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Lipid-rich atherosclerotic plaques are vulnerable, and their rupture can cause the formation of a platelet- and fibrin-rich thrombus leading to myocardial infarction and ischemic stroke. Although the role of plaque-based tissue factor as stimulator of blood coagulation has been recognized, it is not known whether plaques can cause thrombus formation through direct activation of platelets. We is...
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BACKGROUND Several recent studies attempted to classify plaques as those prone to cause clinical manifestations (vulnerable, atheromatous plaques) or those less frequently associated with acute thrombotic complication (stable, fibrous plaques). Defining the cellular and molecular mechanisms that underlie these morphological features remains a challenge. Because interstitial forms of collagen de...
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• We have previously shown, in the atheromatous rabbit aorta, that cholesterol influx can be measured by the accumulation of radioactive cholesterol into the atheromatous lesions, and that, in the period up to 60 days after the commencement of cholesterol feeding, this influx is greater than the net accumulation of cholesterol in the thoracic aorta. The entry of radioactive cholesterol into the...
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ژورنال
عنوان ژورنال: THE JOURNAL OF JAPAN SOCIETY FOR LASER SURGERY AND MEDICINE
سال: 1989
ISSN: 0288-6200
DOI: 10.2530/jslsm1980.10.3_237